Published online Oct 7, 2016. doi: 10.3748/wjg.v22.i37.8435
Peer-review started: June 16, 2016
First decision: July 12, 2016
Revised: July 21, 2016
Accepted: August 8, 2016
Article in press: August 8, 2016
Published online: October 7, 2016
Core tip: Subacute combined degeneration (SCD) of the spinal cord is defined as the degeneration of the posterior and lateral columns of the spinal cord due to vitamin B12 deficiency. Because vitamin B12 deficiency can occur after total gastrectomy, so can SCD. Postoperative assessments have focused on the recurrence of gastric cancer after surgery, with fewer studies focusing on vitamin B12 deficiency, especially because SCD is a long-term complication. This report describes a patient who developed SCD after total gastrectomy for gastric cancer. SCD due to vitamin B12 deficiency should be suspected in patients showing gait disturbance after gastrectomy, even as a long-term complication.