Li-Juan Liu, Ya-Tang Chen, Fan Zhu, Department of Medical Microbiology, School of Medicine, Wuhan University, Wuhan 430071, Hubei Province, China
Shui-Xiang Xie, Department of Pathogenic Biology, Gannan Medical University, Gannan 341000, Jiangxi Province, China
Jing-Ling Xue, Department of Pathology, School of Medicine, Wuhan University, Wuhan 430071, Hubei Province, China
Chuan-Jie Zhang, Department of Children Health Care, Wuhan Medical Care Center for Women and Children, Wuhan 430016, Hubei Province, China
Fan Zhu, Hubei Province Key Laboratory of Allergy and Immunology, Wuhan 430071, Hubei Province, China
Author contributions: Liu LJ and Xie SX equally contributed to this paper with literature review and editing; Chen YT participated in drawing the graphs of the signaling pathways; Xue JL prepared a draft of the “canonical Wnt signaling” portion; Zhang CJ drafted the “non-canonical Wnt signaling” portion; Zhu F was responsible for the design, editing and revision of the article, and approval of the final version.
Supported by National Natural Science Foundation of China, No. 31470264 and No. 81502418; the Key Program of Natural Science Foundation of Hubei Province of China, No. 2014CFA078; the Hubei Provincial Natural Science Foundation of China, No. 2015CFB168 and No. 2012FFB04304; the Scientific Research Innovation Team in Hubei, No. 2015CFA009; the General Financial Grant from the China Postdoctoral Science Foundation, No. 2014M550411; the Fundamental Research Funds for the Central Universities, No. 2042014kf0029; the Tianqing Liver Disease Research Fund of the China Foundation for Hepatitis Prevention and Control, No. TQGB20140250; the Innovation Seed Fund of Wuhan University School of Medicine; the Science and Technology Department Supported Program of Jiangxi Province of China, No. 2010BSA13500; the Science and Technology Project of Education Department of Jiangxi Province of China, No. GJJ11570.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Fan Zhu, PhD, Professor, Department of Medical Microbiology, School of Medicine, Wuhan University, 185 Donghu Road, Wuhan 430071, Hubei Province, China. firstname.lastname@example.org
Telephone: +86-27-68759906 Fax: +86-27-68759906
Received: March 27, 2016
Peer-review started: March 28, 2016
First decision: May 12, 2016
Revised: June 7, 2016
Accepted: July 20, 2016
Article in press: July 20, 2016
Published online: September 7, 2016