Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2016; 22(33): 7463-7477
Published online Sep 7, 2016. doi: 10.3748/wjg.v22.i33.7463
Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective
Hui-Yi Feng, Yang-Chao Chen
Hui-Yi Feng, Yang-Chao Chen, School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong, China
Author contributions: Feng HY and Chen YC wrote the paper.
Supported by General Research Fund, Research Grants Council of Hong Kong, No. CUHK462211, No. CUHK462713 and No. 14102714; National Natural Science Foundation of China, No. 81101888 and No. 8142730; and Direct Grant from CUHK.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Yang-Chao Chen, PhD, School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Shatin, NT, Hong Kong, China.
Telephone: +852-39431100 Fax: +852-26035123
Received: April 9, 2016
Peer-review started: April 10, 2016
First decision: May 12, 2016
Revised: June 30, 2016
Accepted: July 20, 2016
Article in press: July 20, 2016
Published online: September 7, 2016
Core Tip

Core tip: Bile acids bridge the gap between risk factors and pancreatic cancer, providing a new horizon in pancreatic cancer carcinogenesis.