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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2016; 22(29): 6726-6735
Published online Aug 7, 2016. doi: 10.3748/wjg.v22.i29.6726
Published online Aug 7, 2016. doi: 10.3748/wjg.v22.i29.6726
Smaller tumor size is associated with poor survival in T4b colon cancer
Ben Huang, Yang Feng, Shao-Bo Mo, San-Jun Cai, Li-Yong Huang, Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai 20032, China
Author contributions: Huang B and Feng Y contributed equally to this work; Cai SJ and Huang LY are responsible for the study conception and design; Mo SB acquired the data; Huang B and Feng Y analyzed the data and wrote the manuscript.
Institutional review board statement: The study was reviewed and approved by the Fudan University Shanghai Cancer Center Ethical Committee and Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li-Yong Huang, MD, PhD, Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, 270 Dong’an Road, Shanghai 20032, China. hly_981@163.com
Telephone: +86-21-6417 4774 Fax: +86-21-6417 4774
Received: March 24, 2016
Peer-review started: March 25, 2016
First decision: May 12, 2016
Revised: May 25, 2016
Accepted: June 15, 2016
Article in press: June 15, 2016
Published online: August 7, 2016
Peer-review started: March 25, 2016
First decision: May 12, 2016
Revised: May 25, 2016
Accepted: June 15, 2016
Article in press: June 15, 2016
Published online: August 7, 2016
Core Tip
Core tip: In contrast to the association of larger tumor size with poor cancer-specific survival (CSS) in colon cancer patients overall, this study suggested that smaller tumor size was associated with poor CSS in the T4bN0-2M0 subpopulation, particularly in the T4bN0M0 subgroup.