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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2016; 22(25): 5831-5836
Published online Jul 7, 2016. doi: 10.3748/wjg.v22.i25.5831
Published online Jul 7, 2016. doi: 10.3748/wjg.v22.i25.5831
Hemostatic effect of topical hemocoagulase spray in digestive endoscopy
Tao Wang, Dan-Na Wang, Wen-Tian Liu, Zhong-Qing Zheng, Xin Chen, Wei-Li Fang, Shu Li, Li Liang, Bang-Mao Wang, Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin 300052, China
Author contributions: Wang T, Wang DN, Liu WT and Wang BM designed the research; Wang T, Liu WT, Zheng ZQ, Chen X, Fang WL, Li S, Liang L and Wang BM took part in this study as endoscopic operators or assistants; Wang T, Wang DN, Liu WT and Wang BM analyzed the data; Wang T, Wang DN and Wang BM wrote the paper and gave final approval of the version to be published.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Tianjin Medical University General Hospital.
Clinical trial registration statement: This study has not been registered temporarily.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest in relation to this manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Bang-Mao Wang, Professor, Department of Gastroenterology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China. wangt1976@126.com
Telephone: +86-22-60363800
Received: March 13, 2016
Peer-review started: March 13, 2016
First decision: March 31, 2016
Revised: April 21, 2016
Accepted: May 4, 2016
Article in press: May 4, 2016
Published online: July 7, 2016
Peer-review started: March 13, 2016
First decision: March 31, 2016
Revised: April 21, 2016
Accepted: May 4, 2016
Article in press: May 4, 2016
Published online: July 7, 2016
Core Tip
Core tip: In this study, we evaluated the hemostatic effect of topical hemocoagulase spray in digestive endoscopy. There was no significant difference in the rate of perforation between the study and control groups. There was no significant difference in the rate of successful hemostasis between the two groups, but the rates of late bleeding and overall complications of the hemocoagulase group were significantly lower than the 8% norepinephrine group. The surgical field was clearer, the bleeding site was more easily identified, and the wound was cleaner in the study group.