Adjuvant sorafenib after heptectomy for Barcelona Clinic Liver Cancer-stage C hepatocellular carcinoma patients
Feng Xia, Li-Li Wu, Hong-Bo Huan, Xu-Dong Wen, Kuan-Sheng Ma, Xiao-Wu Li, Ping Bie, Institute of Hepatobiliary Surgery, Southwest Hospital, Southwest Cancer Center, Third Military Medical University, Chongqing 400038, China
Wan-Yee Lau, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
Author contributions: Xia F and Wu LL contributed equally to the study; Xia F, Lau WY and Bie P contributed to study conception and design; Wu LL, Huan HB and Wen XD contributed to acquisition of data; Xia F, Lau WY and Li XW contributed to analysis and interpretation of data; Xia F and Wu LL drafted the manuscript; Lau WY and Bie P made critical revision of the manuscript for important intellectual content; Xia F, Wu LL and Wen XD made statistical analysis; Xia F and Bie P obtained funding and supervised the study.
Supported by Key Laboratory of Tumor Immunology and Pathology of Ministry of Education No. 2012jsz108; and the National Natural Sciences Foundation of China No. 81272224.
Institutional review board statement: This study was carried out with pre-approval given by the Ethics Committee of the Southwest Hospital, in accordance with its conformation to the ethical guidelines of the 1975 Helsinki Declaration.
Informed consent statement: Written informed consent was obtained from all patients for their data to be used for research purposes.
Conflict-of-interest statement: The authors who have taken part in this study declared that they do not have anything to disclose regarding funding or conflict of interest with respect to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Feng Xia, MD, PhD, Professor of Surgery, Institute of Hepatobiliary Surgery, Southwest Hospital, Southwest Cancer Center, Third Military Medical University, No. 30 Gaotanyanzhengjie, Chongqing 400038, China. firstname.lastname@example.org
Telephone: +86-23-68765797 Fax: +86-23-65462170
Received: March 4, 2016
Peer-review started: March 7, 2016
First decision: March 21, 2016
Revised: March 27, 2016
Accepted: April 20, 2016
Article in press: April 20, 2016
Published online: June 21, 2016