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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2016; 22(2): 557-566
Published online Jan 14, 2016. doi: 10.3748/wjg.v22.i2.557
Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer
Katsuhiko Nosho, Yasutaka Sukawa, Yasushi Adachi, Miki Ito, Kei Mitsuhashi, Hiroyoshi Kurihara, Shinichi Kanno, Itaru Yamamoto, Keisuke Ishigami, Hisayoshi Igarashi, Reo Maruyama, Kohzoh Imai, Hiroyuki Yamamoto, Yasuhisa Shinomura
Katsuhiko Nosho, Yasutaka Sukawa, Yasushi Adachi, Miki Ito, Kei Mitsuhashi, Hiroyoshi Kurihara, Shinichi Kanno, Itaru Yamamoto, Keisuke Ishigami, Hisayoshi Igarashi, Yasuhisa Shinomura, Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan
Reo Maruyama, Department of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan
Kohzoh Imai, Division of Cancer Research, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan
Hiroyuki Yamamoto, Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki 216-8511, Japan
Author contributions: Nosho K designed the report, analyzed the data and wrote the manuscript; Adachi Y and Maruyama R analyzed the data; Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K and Igarashi H performed experiments; Sukawa Y, Adachi Y, Imai K, Yamamoto H and Shinomura Y edited the manuscript.
Supported by Japanese Society of Gastroenterology Research Foundation (to Nosho K); Pancreas Research Foundation of Japan (to Nosho K); Medical Research Encouragement Prize of The Japan Medical Association (to Nosho K); The Japan Society for the Promotion of Science Challenging Exploratory Research, grant No. 25670371 (to Shinomura Y); and Ono Cancer Research Foundation (to Ito M).
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Katsuhiko Nosho, MD, PhD, Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo 060-8543, Japan. nosho@sapmed.ac.jp
Telephone: +81-11-6112111 Fax: +81-11-6112282
Received: June 30, 2015
Peer-review started: July 4, 2015
First decision: September 11, 2015
Revised: September 25, 2015
Accepted: November 13, 2015
Article in press: November 13, 2015
Published online: January 14, 2016
