Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 7, 2016; 22(1): 369-378
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.369
Capsule endoscopy: The road ahead
Ana-Maria Singeap, Carol Stanciu, Anca Trifan
Ana-Maria Singeap, Anca Trifan, Gastroenterology and Hepatology Institute, “Gr. T. Popa” University of Medicine and Pharmacy, “St. Spiridon” Emergency Hospital, 700111 Iasi, Romania
Carol Stanciu, Gastroenterology and Hepatology Institute, “St. Spiridon” Emergency Hospital, 700111 Iasi, Romania
Author contributions: Singeap AM, Stanciu C and Trifan A contributed equally to the conception and design of the review; Singeap AM performed acquisition of data; Stanciu C analyzed the data, coordinated the manuscript drafting and revised it critically; Trifan A participated in the analysis and interpretation of data, and critically revised the manuscript for important intellectual content; all authors read and approved the final version of the manuscript.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Carol Stanciu, MD, FRCP, Professor, Gastroenterology and Hepatology Institute, “St. Spiridon” Emergency Hospital, Independentei 1, 700111 Iasi, Romania.
Telephone: +40-732-402860 Fax: +40-232-246611
Received: May 5, 2015
Peer-review started: May 9, 2015
First decision: July 19, 2015
Revised: August 4, 2015
Accepted: September 30, 2015
Article in press: September 30, 2015
Published online: January 7, 2016
Core Tip

Core tip: Since its introduction into clinical practice 15 years ago, small bowel capsule endoscopy (CE) has revolutionized direct endoscopic imaging of the gut. During this time, CE has gained tremendous popularity among gastroenterologists, and a vast research pertaining to its different aspects has been published. Dedicated esophageal and colon CE have expanded the field of application to upper and lower gastrointestinal disorders. However, besides its recognized advantages, CE also has several limitations such as the lack of therapeutic capabilities, the inability to obtain biopsies and control its locomotion. Active research is in progress to overcome the current limitations, while the latest advances in CE technology enable us to look forward to a next generation CE capable of performing both diagnostic and therapeutic procedures. This review summarizes the literature that prognosticates about the future of CE.