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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 7, 2015; 21(45): 12981-12986
Published online Dec 7, 2015. doi: 10.3748/wjg.v21.i45.12981
Published online Dec 7, 2015. doi: 10.3748/wjg.v21.i45.12981
Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier
Mu-Hsien Lee, Hao-Tsai Cheng, Hsin-Chih Huang, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 333, Taiwan
Yu-Ching Lin, Department of Intervention and Imaging, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taipei 105, Taiwan
Wen-Yu Chuang, Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taipei 105, Taiwan
Hsiao-Wen Kao, Department of Hematology-Oncology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taipei 105, Taiwan
Author contributions: Lee MH wrote the paper; Cheng HT, Huang HC and Kao HW designed the study; Lin YC reviewed the images; and Chuang WY reviewed the pathological reports.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Chang Gung Hospital (No. 104-5688B).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to enrollment in the study.
Conflict-of-interest statement: The authors have no financial disclosures to declare and no conflicts of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hao-Tsai Cheng, MD, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 5 Fu-Shin Street, Kweishan, Taoyuan 333, Taiwan. howardandbetty@yahoo.com.tw
Telephone: +886-3-3281200-8108 Fax: +886-3-3272236
Received: June 28, 2015
Peer-review started: June 28, 2015
First decision: July 19, 2015
Revised: August 24, 2015
Accepted: September 30, 2015
Article in press: September 30, 2015
Published online: December 7, 2015
Peer-review started: June 28, 2015
First decision: July 19, 2015
Revised: August 24, 2015
Accepted: September 30, 2015
Article in press: September 30, 2015
Published online: December 7, 2015
Core Tip
Core tip: The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin’s lymphoma in the liver is rare. The risk factors include hepatitis virus infection, liver cirrhosis and antineoplastic therapy. This case report presents a rare case of HCC and mantle cell lymphoma in the liver. Only hepatitis B virus infection is identified. “Tumor to tumor metastasis” is noted in the pathologic findings. The literature is also reviewed.