Published online Nov 21, 2015. doi: 10.3748/wjg.v21.i43.12482
Peer-review started: May 12, 2015
First decision: August 25, 2015
Revised: September 15, 2015
Accepted: October 17, 2015
Article in press: October 20, 2015
Published online: November 21, 2015
Core tip: Cooperative laparoscopic and endoscopic surgery for the resection of upper gastrointestinal tumors combines the advantages of intraluminal and extraluminal approach: precise lesion localization, safe excision and reconstruction. It has been used for the resection of benign submucosal tumors and Gastrointestinal stromal tumors. Novel techniques like inverted laparoscopic endoscopic cooperative surgery, laparoscopic assisted endoscopic full thickness resection, clean non exposure technique and non-exposed endoscopic wall-inversion surgery have emerged for the minimally invasive treatment of early gastric cancer. Their oncologic principles are sound and the first results encouraging. Soon, the close collaboration of laparoscopic and endoscopic teams will be “conditio sine qua non” for the institutions that seek excellence in the treatment of upper gastrointestinal neoplasias.