Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2015; 21(27): 8284-8292
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8284
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8284
MicroRNAs potential utility in colon cancer: Early detection, prognosis, and chemosensitivity
Michael Hollis, Lakshmi Shankar Chaturvedi, Sahil Gambhir, Dinesh Vyas, Department of Surgery, College of Human Medicine, Michigan State University, East Lansing, MI 48912, United States
Kavitha Nair, Department of Medicine, Emory University, Atlanta, GA 30322, United States
Arpita Vyas, Pediatrics, College of Human Medicine, Michigan State University, East Lansing, MI 49503, United States
Author contributions: Hollis M and Vyas A contributed equally to this work; they designed research, analyzed data, and wrote the paper; Nair K and Gambhir S contributed in research; Vyas D contributed in data and conceptualization; all authors finally approved the manuscript.
Conflict-of-interest statement: The authors declare no conflict of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dinesh Vyas, MD, MS, FICS, Department of Surgery, College of Human Medicine, Michigan State University, 1200 East Michigan Avenue, Suite 655, MI 48912, United States. dinesh.vyas@hc.msu.edu
Telephone: +1-517-2672491 Fax: +1-517-2672488
Received: January 20, 2015
Peer-review started: January 20, 2015
First decision: March 10, 2015
Revised: March 24, 2015
Accepted: May 27, 2015
Article in press: May 27, 2015
Published online: July 21, 2015
Peer-review started: January 20, 2015
First decision: March 10, 2015
Revised: March 24, 2015
Accepted: May 27, 2015
Article in press: May 27, 2015
Published online: July 21, 2015
Core Tip
Core tip: Specific microRNA (miRNA) have potential to display the effects of a tumor suppressor or oncogene. Altered miRNA expression is found in colon cancer and patterns of miRNA expression correlate with its detection and outcome.