Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 7, 2015; 21(1): 139-154
Published online Jan 7, 2015. doi: 10.3748/wjg.v21.i1.139
Pharmacological therapy used in the elimination of Helicobacter pylori infection: A review
Ariolana A dos Santos, Adriana A Carvalho
Ariolana A dos Santos, Adriana A Carvalho, Department of Pharmacy, Federal University of Sergipe, Campus Lagarto, 49400-00 Lagarto, Sergipe, Brazil
Author contributions: dos Santos AA and Carvalho AA contributed equally to this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Adriana A Carvalho, MD, PhD, Professor of Pharmacy, Department of Pharmacy, Federal University of Sergipe, Campus Lagarto, Rua Padre Alvares Pitangueira, no.248 Centro, 49400-00 Lagarto, Sergipe, Brazil.
Telephone: +55-91-916944 Fax: +55-91-916944
Received: July 13, 2014
Peer-review started: July 13, 2014
First decision: August 6, 2014
Revised: August 16, 2014
Accepted: September 18, 2014
Article in press: September 19, 2014
Published online: January 7, 2015
Core Tip

Core tip:Helicobacter pylori is a bacterium that is commonly found in the stomach and is capable of causing a number of digestive problems, including ulcers and stomach cancer. Over the past few years, the efficacy of conventional therapy has decreased. However, new therapies are not commonly accepted as first-line treatments in some countries because of a lack of national validation studies. This review aimed to report studies demonstrating the effectiveness of different non-conventional therapies and comparing them with conventional triple therapy.