Prospective Study
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World J Gastroenterol. Dec 21, 2014; 20(47): 17993-18000
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17993
Poor agreement between endoscopists and gastrointestinal pathologists for the interpretation of probe-based confocal laser endomicroscopy findings
Shajan Peter, Leona Council, Ji Young Bang, Helmut Neumann, Klaus Mönkemüller, Shyam Varadarajulu, Charles Melbern Wilcox
Shajan Peter, Ji Young Bang, Helmut Neumann, Klaus Mönkemüller, Shyam Varadarajulu, Charles Melbern Wilcox, Division of Gastroenterology and Hepatology, University of Alabama, Birmingham, AL 35294-0012, United States
Leona Council, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294-0012, United States
Helmut Neumann, Department of Medicine 1, University of Erlangen-Nuremberg, 91054 Erlangen, Germany
Author contributions: All authors contributed to the manuscript.
Correspondence to: Shajan Peter, MD, Associate Professor, Division of Gastroenterology and Hepatology, University of Alabama, 1808 7th Avenue South, BDB 380, Birmingham, AL 35294-0012, United States. shajan@uab.edu
Telephone: +1-205-9964059 Fax: +1-205-9756381
Received: January 24, 2014
Revised: April 3, 2014
Accepted: July 15, 2014
Published online: December 21, 2014
Core Tip

Core tip: Probe-based confocal endomicroscopy (pCLE) has emerged as a valuable tool in the diagnosis and management of gastrointestinal disorders. It has helped the endoscopist to make real time decisions and targeted biopsies. Histopathology still remains the gold standard. We compared the interpretation of pCLE findings between an endoscopist and a dedicated gastrointestinal pathologist and found there was a discrepency in the intepretation of the same findings between them. This is interesting as the endoscopist has a different approach of intepreting real time endomicroscopy compared to that of a pathologist.