Procalcitonin and intestinal ischemia: A review of the literature

doi:10.3748/wjg.v20.i47.17773

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 21, 2014; 20(47): 17773-17778
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17773

Procalcitonin and intestinal ischemia: A review of the literature

Cyril Cosse, Charles Sabbagh, Saïd Kamel, Antoine Galmiche, Jean-Marc Regimbeau

Cyril Cosse, Charles Sabbagh, Saïd Kamel, INSERM U1088, Jules Verne University of Picardie, 80054 Amiens, France

Cyril Cosse, Charles Sabbagh, Jean-Marc Regimbeau, Department of Digestive and Oncological Surgery, Amiens University Hospital, Jules Verne University of Picardie, Place Victor Pauchet, F-80054 Amiens cedex 01, France

Cyril Cosse, Jean-Marc Regimbeau, Clinical Research Center, Amiens University Hospital, 80054 Amiens Cedex 01, France

Saïd Kamel, Antoine Galmiche, Department of Biochemistry, Amiens University Hospital, Jules Verne University of Picardie, F-80054 Amiens, France

Jean-Marc Regimbeau, EA4294, Jules Verne University of Picardie, F-80054 Amiens, France

Author contributions: Cosse C and Regimbeau JM contributed equally to this work; Cosse C, Sabbagh C, Kamel S, Galmiche A and Regimbeau JM designed the review; Cosse C, Sabbagh C and Regimbeau JM performed the review; Cosse C, Sabbagh C, Kamel S, Galmiche A and Regimbeau JM analyzed the data; Cosse C, Sabbagh C and Regimbeau JM wrote the review; Kamel S and Galmiche A approved the review.

Correspondence to: Jean-Marc Regimbeau, Professor, Department of Digestive and Oncological Surgery, Amiens University Hospital, Jules Verne University of Picardie, Place Victor Pauchet, F-80054 Amiens cedex 01, France. regimbeau.jean-marc@chu-amiens.fr

Telephone: +33-322-668301 Fax: +33-322-668680

Received: May 15, 2014
Revised: July 7, 2014
Accepted: August 13, 2014
Published online: December 21, 2014

Core Tip

Core tip: The serum procalcitonin level is clinically relevant for the diagnosis of intestinal ischemia. In the diagnosis of intestinal ischemia, procalcitonin’s sensitivity is greater than 70% and its negative predictive value is greater than 80%.