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World J Gastroenterol. Nov 21, 2014; 20(43): 16252-16257
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16252
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16252
Characteristics and long-term prognosis of patients with rectal neuroendocrine tumors
Yihebali Chi, Feng Du, Hong Zhao, Jin-Wan Wang, Jian-Qiang Cai, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China
Author contributions: Chi Y and Du F contributed to writing the manuscript; Chi Y was responsible for the study design and for collecting the primary data and its translation; Du F was involved in patient follow-up, interpretation and analysis of the data, and the initial work in preparing the manuscript; all authors contributed to critical review of the manuscript and all read and approved the final version.
Correspondence to: Jian-Qiang Cai, Professor, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, No. 17 Panjiayuannanli, Chaoyang District, Beijing 100021, China. yihebalichi@hotmail.com
Telephone: +86-10-88859155 Fax: +86-10-88859155
Received: April 8, 2014
Revised: June 9, 2014
Accepted: July 16, 2014
Published online: November 21, 2014
Revised: June 9, 2014
Accepted: July 16, 2014
Published online: November 21, 2014
Core Tip
Core tip: An analysis of the clinicopathologic characteristics of a group of 57 patients with pathologically-confirmed diagnoses of rectal neuroendocrine tumors showed that these tumors mostly occur in the middle and lower rectum. The most common tumor-node-metastasis stage found was stage I, and lymph node or distant metastases were rarely seen. The major pathological type was a typical carcinoid tumor. Transanal extended excisions generally produced satisfactory curative effects, and the 5-year survival rate was as high as 88.6%. A multivariate analysis of the patient and tumor characteristics indicated that the pathological type is an independent prognostic factor.