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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2014; 20(39): 14488-14494
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14488
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14488
Split-dose vs same-day reduced-volume polyethylene glycol electrolyte lavage solution for morning colonoscopy
Wah-Kheong Chan, Sanjiv Mahadeva, Khean-Lee Goh, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
Najib Azmi, Faculty of Medicine, Islamic Science University of Malaysia, Bandar Baru Nilai, Nilai 71800, Negeri Sembilan, Malaysia
Author contributions: Chan WK was involved in study concept and design, data collection, analysis and interpretation, drafting of the manuscript, and revision of the manuscript; Azmi N was involved in data collection; Mahadeva S and Goh KL was involved in revision and final approval of the manuscript.
Supported by University of Malaya Research Grant, Project No. RG536-13HTM
Correspondence to: Wah-Kheong Chan, MBBS, MRCP, Associate Professor and Consultant Gastroenterologist, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. wahkheong2003@hotmail.com
Telephone: +60-379-492965 Fax: +60-379-604190
Received: February 9, 2014
Revised: March 21, 2014
Accepted: June 14, 2014
Published online: October 21, 2014
Revised: March 21, 2014
Accepted: June 14, 2014
Published online: October 21, 2014
Core Tip
Core tip: In this study of adult patients undergoing morning colonoscopy, split-dose administration of reduced-volume polyethylene glycol electrolyte lavage solution (PEG-ELS) plus bisacodyl was found to be as effective but better tolerated than whole-dose taken on the same morning. To the best of our knowledge, this is the first time these regimes have been compared. Moreover, bowel preparation using split-dose reduced-volume PEG-ELS has not been reported before although there have been many studies comparing split-dose and previous-evening whole-dose regimes using larger volumes of PEG-ELS. We believe the findings of this study will be of interest to those in related fields.