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World J Gastroenterol. Aug 28, 2014; 20(32): 11321-11325
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11321
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11321
Electrocardiograms changes in children with functional gastrointestinal disorders on low dose amitriptyline
Ashish Chogle, Miguel Saps, Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ann and Robert Lurie Children’s Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States
Author contributions: Chogle A contributed to analysis and interpretation of data, drafting of the manuscript and revision of the manuscript; Saps M provided the conception and design, acquisition of data and revision of the manuscript.
Correspondence to: Ashish Chogle, MD, MPH, Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ann and Robert Lurie Children’s Hospital of Chicago, Feinberg School of Medicine, Northwestern University, 225 E Chicago Ave, Chicago, IL 60611, United States. achogle@luriechildrens.org
Telephone: +1-312-2274000 Fax: +1-312-2279645
Received: December 20, 2013
Revised: March 28, 2014
Accepted: May 28, 2014
Published online: August 28, 2014
Revised: March 28, 2014
Accepted: May 28, 2014
Published online: August 28, 2014
Core Tip
Core tip: Information on electrocardiogram changes in children who are on low dose amitriptyline for treatment of abdominal pain associated-functional gastrointestinal disorders (AP-FGIDs) is sparse. To better understand the effects of low dose amitriptyline on cardiac conduction in children, we reviewed the electrocardiogram findings before and after initiation of amitriptyline. We found that use of low dose amitriptyline in children with AP-FGIDs was not associated with clinically significant changes in cardiac conduction.