Randomized Controlled Trial
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World J Gastroenterol. Aug 21, 2014; 20(31): 11012-11018
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.11012
Muscovite is protective against non-steroidal anti-inflammatory drug-induced small bowel injury
Chen Huang, Bin Lu, Yi-Hong Fan, Lu Zhang, Ning Jiang, Shuo Zhang, Li-Na Meng
Chen Huang, Bin Lu, Yi-Hong Fan, Lu Zhang, Ning Jiang, Shuo Zhang, Li-Na Meng, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Lu B designed and supervised the study; Huang C performed the majority of the survey and interpreted the data as well as wrote the manuscript; Fan YH, Zhang L, Jiang N, Zhang S analyzed the video; Meng LN performed the organization and management of volunteers; all authors have read and approved the final version to be published.
Supported by Medical and Health Scientific Research Foundation of Zhejiang Province, China, No. 20112DA022
Correspondence to: Bin Lu, MD, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. lvbin@medmail.com.cn
Telephone: +86-571-87032028 Fax: +86-571-87077785
Received: December 23, 2013
Revised: February 16, 2014
Accepted: April 30, 2014
Published online: August 21, 2014
Core Tip

Core tip: This is a randomized, open-label, controlled clinical trial to evaluate the incidence of small bowel damage by capsule endoscopy in healthy participants who received treatment with the nonsteroidal anti-inflammatory drug (NSAID) diclofenac and the effect of muscovite in preventing NSAID-induced small bowel injury.