Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2014; 20(31): 10994-10999
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10994
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10994
Clinical and endoscopic characteristics of drug-induced esophagitis
Su Hwan Kim, Ji Bong Jeong, Ji Won Kim, Seong-Joon Koh, Byeong Gwan Kim, Kook Lae Lee, Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul 156-707, South Korea
Mee Soo Chang, Department of Pathology, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul 156-707, South Korea
Jong Pil Im, Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 110-744 Seoul, South Korea
Hyoun Woo Kang, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, 410-773 Gyeonggi-do, South Korea
Cheol Min Shin, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, 463-707 Gyeonggi-do, South Korea
Author contributions: Kim SH and Jeong JB contributed equally to this work; Kim SH and Jeong JB performed the data analysis and wrote the paper; Kim JW designed this study and supervised the entire research; Koh SJ, Kim BG and Lee KL revised the manuscript for intellectual content; Chang MS performed the histopathological analysis; Kim SH, Jeong JB, Im JP, Kang HW and Shin CM obtained the data; all authors reviewed and approved the final version of the manuscript.
Correspondence to: Ji Won Kim, MD, PhD, Associate Professor, Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 5 Gil 20, Boramae-Road, Dongjak-Gu, 156-707 Seoul, South Korea. kjwjor@snu.ac.kr
Telephone: +82-2-870-2221 Fax: +82-2-870-3863
Received: March 16, 2014
Revised: April 30, 2014
Accepted: May 25, 2014
Published online: August 21, 2014
Revised: April 30, 2014
Accepted: May 25, 2014
Published online: August 21, 2014
Core Tip
Core tip: This study investigated the clinical characteristics of drug-induced esophagitis, such as the main symptoms, common endoscopic findings and main causative agents. Uniquely, kissing ulcers were observed in 43.6% of drug-induced esophagitis, which is a higher rate than in the previous reports. This might be helpful in diagnosing this rare disease. To the best of our knowledge, the present study is the first to compare the histopathological features between drug-induced esophagitis group and reflux esophagitis group.