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World J Gastroenterol. Aug 21, 2014; 20(31): 10651-10657
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10651
Role of cardiovascular intervention as a bridge to liver transplantation
Zankhana Raval, Matthew E Harinstein, James D Flaherty
Zankhana Raval, James D Flaherty, Bluhm Cardiovascular Institute, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, United States
Matthew E Harinstein, University of Pittsburgh Medical Center Heart and Vascular Institute, Pittsburgh, PA 15219, United States
Author contributions: Raval Z contributed to the study idea, study design, literature search, and manuscript writing; Harinstein ME contributed to the manuscript writing and final revision of the article; Flaherty JD contributed to the study idea, literature search, manuscript writing and final revision of the article.
Correspondence to: James D Flaherty, MD, Bluhm Cardiovascular Institute, Feinberg School of Medicine of Northwestern University, 676 North Saint Clair St. Suite 600, Chicago, IL 60611, United States. jflahert@nmh.org
Telephone: +1-312-9268948 Fax: +1-312-6949430
Received: October 17, 2013
Revised: January 11, 2014
Accepted: April 1, 2014
Published online: August 21, 2014
Core Tip

Core tip: The population of liver transplant candidates is rapidly evolving with respect to advanced age, etiology and co-morbidities. Consequently, the cardiovascular risk profiles of these candidates have increased. At the same time, the availability of interventions, both mechanical and pharmacologic, for cardiovascular conditions has allowed previously unsuitable candidates to go on to liver transplantation. Therefore, it is imperative to understand how to define the cardiovacular risk profile of liver transplant candidates and the pre-transplant treatment options available to them.