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World J Gastroenterol. Jan 21, 2014; 20(3): 639-646
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.639
Impairment of ghrelin synthesis in Helicobacter pylori-colonized stomach: New clues for the pathogenesis of H. pylori-related gastric inflammation
Omero Alessandro Paoluzi, Del Vecchio Giovanna Blanco, Roberta Caruso, Ivan Monteleone, Giovanni Monteleone, Francesco Pallone
Omero Alessandro Paoluzi, Roberta Caruso, Ivan Monteleone, Giovanni Monteleone, Francesco Pallone, Giovanna Del Vecchio Blanco, Department of Systems Medicine, University of Rome “Tor Vergata”, 00133 Rome, Italy
Author contributions: Paoluzi OA and Del Vecchio Blanco G contributed equally to this work; all authors contributed to the manuscript.
Correspondence to: Dr. Omero Alessandro Paoluzi, Department of Systems Medicine, University of Rome “Tor Vergata”, Viale Oxford 81, 00133 Roma, Italy. omeroalessandro.paoluzi@ptvonline.it
Telephone: +39-6-20900969 Fax: +39-6-20903738
Received: October 4, 2013
Revised: November 14, 2013
Accepted: December 5, 2013
Published online: January 21, 2014
Core Tip

Core tip: The review reports current statements about relationship between gastric ghrelin expression and Helicobacter pylori infection. Data present in the literature and emerging from a very recent our study on the anti-inflammatory role of ghrelin and T helper 1 cell response in the stomach during Helicobacter pylori infection are included.