Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.9732
Revised: February 13, 2014
Accepted: March 12, 2014
Published online: August 7, 2014
Core tip: This is a review underlining the importance of biomarkers in the treatment of metastatic colorectal cancer. All most recent findings are described to offer a contribution to define a correct approach to anti-epidermal growth factor receptor based treatment.