Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.9633
Revised: April 20, 2014
Accepted: May 19, 2014
Published online: August 7, 2014
Core tip: Challenges and opportunities will characterise the story of hepatitis C virus (HCV) infection also in the new era. Despite the great therapeutic advances, improvements in HCV surveillance, epidemiological mapping, testing, prevention and therapy are urgently needed. Currently HCV vaccine candidates have shown promising results in animal models and data from clinical phase 1/2 trials are expected. Predictors of response to therapy represent a chance for modulated and personalized treatment management, when also very potent therapies will be available. The ultimate goal of global HCV control will be achieved with the joint efforts of researchers and public health workers.