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World J Gastroenterol. Jul 28, 2014; 20(28): 9292-9298
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9292
Familial colorectal cancer: A review
Franco Armelao, Giovanni de Pretis
Franco Armelao, Giovanni de Pretis, Department of Gastroenterology, Ospedale Santa Chiara, Azienda Provinciale per i Servizi Sanitari, 38122 Trento, Italy
Author contributions: Armelao F and de Pretis G wrote this review.
Correspondence to: Franco Armelao, MD, Department of Gastroenterology, Ospedale Santa Chiara, Azienda Provinciale per i Servizi Sanitari, Largo Medaglie d’Oro, 38122 Trento, Italy. franco.armelao@apss.tn.it
Telephone: +39-461-903954 Fax: +39-461-903446
Received: September 25, 2013
Revised: January 17, 2014
Accepted: April 27, 2014
Published online: July 28, 2014
Core Tip

Core tip: Although first degree relatives of patients with colorectal cancer have a 2- to 4- increased risk for this disease and screening guidelines are recommended in this moderate risk population, the optimal screening strategy has to be determined.