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World J Gastroenterol. Jul 14, 2014; 20(26): 8717-8721
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8717
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8717
Acute abdomen: Rare and unusual presentation of right colic xanthogranulomatosis
Paola Addario Chieco, Laura Antolino, Valentina Giaccaglia, Francesca Centanini, Gaetano Vincenzo Cunsolo, Alessandra Sparagna, Vincenzo Ziparo, Department of General Surgery, General Surgery 1 Unit, S. Andrea University Hospital, 00189 Rome, Italy
Paola Addario Chieco, Laura Antolino, Valentina Giaccaglia, Francesca Centanini, Gaetano Vincenzo Cunsolo, Alessandra Sparagna, Vincenzo Ziparo, Stefania Uccini, Department of Pathology, S. Andrea University Hospital, 00189 Rome, Italy
Author contributions: Antolino L, Centanini F, Cunsolo GV and Sparagna A contributed to acquisition of the data; Antolino L and Giaccaglia V contributed to analysis and interpretation of the data; Antolino L, Giaccaglia V, Cunsolo GV, Sparagna A and Uccini S contributed to drafting of the manuscript; Addario Chieco P, Giaccaglia V and Ziparo V contributed to critical revision of the paper.
Correspondence to: Paola Addario Chieco, MD, Department of General Surgery, General Surgery 1 Unit, S. Andrea University Hospital, Via di Grottarossa 1085, 00189 Rome, Italy. paddariochieco@ospedalesantandrea.it
Telephone: +39-6-33775693 Fax: +39-6-33775228
Received: February 1, 2013
Revised: April 23, 2013
Accepted: May 18, 2013
Published online: July 14, 2014
Revised: April 23, 2013
Accepted: May 18, 2013
Published online: July 14, 2014
Core Tip
Core tip: Xanthogranulomatous inflammation (XGI) is a disease of unknown origin, most frequently described in the kidney and gallbladder, and extremely rare in the colon. The extension of inflammation to the surrounding tissues may lead to misdiagnosis as cancer. We report the case of a 56-year-old woman presenting to the Emergency Department with pain, increased levels of acute-phase proteins, and a palpable mass in the right lower abdominal quadrant. Computed tomography showed a large cecal mass with necrotic areas and enlarged lymph nodes. Due to suspicion of malignancy and worsening of the clinical conditions, she underwent right colectomy. Pathology revealed XGI of the ileocecal valve.