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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2014; 20(26): 8631-8637
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8631
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8631
Impact of tumor location on clinical outcomes of gastric endoscopic submucosal dissection
Ji Young Yoon, Choong Nam Shim, Sook Hee Chung, Wan Park, Hyunsoo Chung, Hyuk Lee, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Jun Chul Park, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul 120-752, South Korea
Author contributions: Yoon JY and Shim CN contributed equally to this work; all the authors participated in this study.
Supported by A Faculty Research Grant of Yonsei University College of Medicine for 2010, No. 6-2010-0145
Correspondence to: Jun Chul Park, MD, Assistant Professor, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. junchul75@yuhs.ac
Telephone: +82-2-22282272 Fax: +82-2-3936884
Received: November 5, 2013
Revised: February 13, 2014
Accepted: March 12, 2014
Published online: July 14, 2014
Revised: February 13, 2014
Accepted: March 12, 2014
Published online: July 14, 2014
Core Tip
Core tip: Location of the tumor is one of the most important clinical factors for complete resection and complications of endoscopic submucosal dissection (ESD) for early gastric cancer. Nonetheless, few studies have evaluated clinicopathologic outcomes of ESD according to the subdivision of tumor location. Based on our data, posterior wall lesions and upper third lesions were significantly associated with incomplete resection and perforation, respectively. Therefore, endoscopists should recognize the need for more advanced endoscopic techniques when performing ESD for lesions located in the upper third or posterior wall of the stomach to decrease the rate of serious complications and improve clinical outcomes.