Retrospective Study
Copyright ©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2014; 20(26): 8624-8630
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8624
Selection of appropriate endoscopic therapies for duodenal tumors: An open-label study, single-center experience
Satohiro Matsumoto, Yukio Yoshida
Satohiro Matsumoto, Yukio Yoshida, Department of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan
Author contributions: Matsumoto S conceived and designed the experiments, performed the experiments and analyzed the data; Matsumoto S contributed reagents/materials/analysis tools, wrote the paper; Matsumoto S and Yoshida Y approved the final manuscript.
Correspondence to: Satohiro Matsumoto, MD, PhD, Department of Gastroenterology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya, Saitama 330-8503, Japan.
Telephone: +81-48-6472111 Fax: +81-48-6485188
Received: January 23, 2014
Revised: March 11, 2014
Accepted: April 15, 2014
Published online: July 14, 2014
Core Tip

Core tip: Endoscopic treatment of duodenal lesions is associated with a high incidence of complications. In particular, duodenal endoscopic submucosal dissection (ESD) is technically difficult. Therefore, the indications for duodenal ESD are not yet to be established. This study aimed to determine an appropriate compartmentalization of duodenal ESD or endoscopic mucosal resection (EMR). ESD was associated with a longer procedure time and a higher incidence of intraprocedural perforation; EMR was associated with a lower rate of complete resection. For early duodenal cancer and neuroendocrine tumors, which require en bloc resection, ESD is preferable if en bloc resection by EMR is difficult, while EMR is sufficient for endoscopic treatment of adenomas.