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World J Gastroenterol. Jul 14, 2014; 20(26): 8449-8457
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8449
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8449
Colonic polyps: Is it useful to characterize them with advanced endoscopy?
Maria Lopez-Ceron, Erwin Sanabria, Maria Pellise, Endoscopy Unit, Department of Gastroenterology, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Author contributions: Lopez-Ceron M and Sanabria E performed the literature review and wrote the manuscript; Pellise M contributed to topic selection, critical revision and approval of the final manuscript.
Supported by The CIBERehd (Centro de Investigación Biomédica en Red, enfermedades hepaticas y digestivas) to Sanabria E
Correspondence to: Maria Pellise, MD, PhD, Endoscopy Unit, Department of Gastroenterology, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Villarroel 170, Catalonia, 08036 Barcelona, Spain. mpellise@clinic.ub.es
Telephone: +34-93-2275418 Fax: +34-93-2279387
Received: November 5, 2013
Revised: February 14, 2014
Accepted: March 12, 2014
Published online: July 14, 2014
Revised: February 14, 2014
Accepted: March 12, 2014
Published online: July 14, 2014
Core Tip
Core tip: Endoscopic characterization of colonic polyps by “virtual histology” is a currently accessible tool for identification of lesion type, thus enabling endoscopists to determine optimal treatment strategies. Chromoendoscopy (CE) has shown high accuracy for differentiating polyp histologies (neoplastic vs non-neoplastic) and for estimating the depth of invasion. Furthermore, digital systems such as narrow band imaging are a viable alternative to CE regarding lesion characterization, ease of use, reversibility, and cleanliness.