Case Report
Copyright ©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2014; 20(25): 8288-8291
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8288
Novel therapy for non-cirrhotic hyperammonemia due to a spontaneous splenorenal shunt
Shari S Rogal, Angela Hu, Rupal Bandi, Obaid Shaikh
Shari S Rogal, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, United States
Angela Hu, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States
Rupal Bandi, Department of Radiology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, United States
Obaid Shaikh, Division of Gastroenterology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, United States
Author contributions: All authors contributed to writing and editing the manuscript.
Supported by Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development
Correspondence to: Shari S Rogal, MD, MPH, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, 200 Lothrop Street, M Level, C Wing, PUH, Pittsburgh, PA 15213, United States. rogalss@upmc.edu
Telephone: +1-412-6489115 Fax: +1-412-6489378
Received: October 2, 2013
Revised: December 10, 2013
Accepted: January 14, 2014
Published online: July 7, 2014
Core Tip

Core tip: This is the first reported case of non-portal hypertension associated hepatic encephalopathy related to a large splenorenal shunt that was successfully closed percutaneously with an Amplatzer plug applied to the splenic vein.