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World J Gastroenterol. Jul 7, 2014; 20(25): 8082-8091
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8082
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8082
Oxidative stress as a crucial factor in liver diseases
Halina Cichoż-Lach, Department of Gastroenterology, Medical University of Lublin, 20-094 Lublin, Poland
Agata Michalak, Student of the Second Faculty of Medicine, Medical University of Lublin, 20-059 Lublin, Poland
Author contributions: Cichoż-Lach H and Michalak A contributed equally to this work; Cichoż-Lach H and Michalak A made substantial contributions to the study conception and design, and contributed to the writing of the manuscript.
Correspondence to: Halina Cichoż-Lach, Professor, Department of Gastroenterology, Medical University of Lublin, Jaczewski Str. 8, 20-954 Lublin, Poland. lach.halina@wp.pl
Telephone: +48-60-1377656 Fax: +48-81-4796135
Received: December 6, 2013
Revised: February 8, 2014
Accepted: April 21, 2014
Published online: July 7, 2014
Revised: February 8, 2014
Accepted: April 21, 2014
Published online: July 7, 2014
Core Tip
Core tip: This article focuses on the role of oxidative stress in liver diseases. Redox state constitutes the important background of numerous liver disorders. It participates in the course of inflammatory, metabolic and proliferative liver diseases. An oxidative stress stands for an imbalance between oxidant and antioxidant agents. It may explain pathogenetic aspects of chronic liver diseases. This paper is a review on newest literature in this field. In the light the above we hope that this article is interesting and may contribute to current knowledge.