Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6159
Revised: January 26, 2014
Accepted: March 19, 2014
Published online: May 28, 2014
Core tip: Biliary complications after liver transplantation represent a major challenge. Ischaemic cholangiopathy is a set of disorders characterized by multiple diffuse intrahepatic strictures. Ischaemic cholangiopathy can cause a late graft loss. It becomes more evident after the widespread usage of grafts after circulatory deaths. Awareness of predisposing factors, presentation, diagnosis, and management is mandatory. Prophylaxis is essential by controlling risk factors. Management varies from simple radiological interventions to re-transplantation.