Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6133
Revised: November 1, 2013
Accepted: March 4, 2014
Published online: May 28, 2014
Core tip: Pulmonary metastasectomy is now the accepted treatment of choice in the multimodal management of metastatic colorectal cancer. There is no absolute contraindication for pulmonary metastasectomy as long as complete resection can be achieved. However, there are still many questions regarding the proper indication of pulmonary metastasectomy, for example: How many times can pulmonary metastasectomy be performed for recurrent pulmonary metastases? How many nodules can be resected safely and effectively in patients with recurrent and multiple metastatic nodules? This article reviews the different therapeutic strategies for patients with pulmonary metastases of colorectal cancer, with a particular focus on these questions.