Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6123
Revised: November 30, 2013
Accepted: February 16, 2014
Published online: May 28, 2014
Core tip: Many types of cancer-associated sialoglycoconjugates are produced during oncogenesis or in various stages of malignant transformation. Aberrant expression of sialoglycoconjugates has been evaluated in many histochemical and molecular biological studies. An overview of the current knowledge is crucial to understand its clinicopathological utility in diagnosing and treating colorectal cancer. The biological significance of sialoglycoconjugates in the progression of cancer is also discussed. This review may contribute to expanding the use of cancer-associated sialoglycoconjugates in cancer diagnosis and therapy.