Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6113
Revised: December 26, 2013
Accepted: February 16, 2014
Published online: May 28, 2014
Core tip: In patients with colorectal liver metastases, surgical resection is the treatment of choice. This paper aimed to discuss the goals of surgery, which should be to resect all metastases with negative histological margins while preserving sufficient functional hepatic parenchyma. The paper also discusses treatment options for patients with extensive metastatic disease who would otherwise be unresectable, such as systemic chemotherapy, radiofrequency ablation and preoperative portal vein embolization combined with surgery.