Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.5973
Revised: January 13, 2014
Accepted: April 8, 2014
Published online: May 28, 2014
Core tip: Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is a complex cancer of the liver stemming from the long term infection of the virus. MiRNAs are found to be involved in a multitude of events, ranging from the diagnosis, pathogenesis as well as possibly in the treatment of this cancer. This review explores the current knowledge in understanding the role of miRNAs in HBV-related HCC, and how it is able to regulate, or be regulated, such that important cellular processes may be affected.