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World J Gastroenterol. May 7, 2014; 20(17): 4846-4856
Published online May 7, 2014. doi: 10.3748/wjg.v20.i17.4846
Inflammatory bowel disease and celiac disease: Overlaps and differences
Virginia Pascual, Romina Dieli-Crimi, Natalia López-Palacios, Andrés Bodas, Luz María Medrano, Concepción Núñez
Virginia Pascual, Romina Dieli-Crimi, Luz María Medrano, Concepción Núñez, UGC de Inmunología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
Natalia López-Palacios, Servicio de Digestivo, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
Andrés Bodas, Servicio de Pediatría, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
Author contributions: Pascual V contributed to the extensive literature search and preparation of the first manuscript draft; Dieli-Crimi R contributed to the literature search and preparation of the first manuscript draft; López-Palacios N contributed to the literature search and preparation of the first manuscript draft; Bodas A contributed to the literature search and preparation of the first manuscript draft; Medrano LM contributed to the literature search and preparation of the first manuscript draft; Núñez C contributed to the study idea, literature search, manuscript writing and final revision of the article; all authors approved the manuscript.
Supported by Grants from “Fondo de Investigaciones Sanitarias”, PI11/00614; and “Fundación Eugenio Rodríguez Pascual”
Correspondence to: Concepción Núñez, PhD, UGC de Inmunología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), C/ Profesor Martín Lagos s/n Madrid, 28040 Madrid, Spain. conchita.npardo@gmail.com
Telephone: +34-913-302499 Fax: +34-913-303344
Received: September 27, 2013
Revised: November 20, 2013
Accepted: January 14, 2014
Published online: May 7, 2014
Core Tip

Core tip: Inflammatory bowel disease and celiac disease are two immune-mediated diseases characterized by chronic intestinal inflammation. Recent findings demonstrate shared genetics and functional pathways. We reviewed the extension of these overlaps to other disease features and suggest future research approaches.