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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Apr 28, 2014; 20(16): 4817-4821
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4817
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4817
Gastrointestinal stromal tumor of the ampulla of Vater: A case report
Masayoshi Kobayashi, Nobuto Hirata, So Nakaji, Toshiyasu Shiratori, Hiroyuki Fujii, Eiji Ishii, Department of Gastroenterology, Kameda Medical Center, Chiba 296-0041, Japan
Author contributions: Kobayashi M designed the study and wrote the manuscript; Hirata N and Nakaji S contributed to the manuscript revision; Shiratori T, Fujii H and Ishii E contributed to the literature review and manuscript editing.
Correspondence to: Masayoshi Kobayashi, MD, Department of Gastroenterology, Kameda Medical Center, 929 Higashi-cho, Kamogawa City, Chiba 296-0041, Japan. k-masayoshi@hotmail.co.jp
Telephone: +81-4-70922211 Fax: +81-4-70991131
Received: December 1, 2013
Revised: February 9, 2014
Accepted: March 4, 2014
Published online: April 28, 2014
Revised: February 9, 2014
Accepted: March 4, 2014
Published online: April 28, 2014
Core Tip
Core tip: Gastrointestinal stromal tumor (GIST) usually develops in the stomach and small intestine, and GIST of the ampulla of Vater is extremely rare, with only 11 cases reported in the literature. We report a case of GIST of the ampulla of Vater in a 36-year-old, previously healthy man who presented with a brief loss of consciousness. A gastroduodenal endoscopy revealed a submucosal tumor with central ulceration at the ampulla of Vater. Biopsies were collected from the ulcerative lesion, and the tumor was diagnosed as a GIST. The patient underwent pancreatoduodenectomy. The operative specimen revealed a 2.2-cm GIST with 1 mitosis per 50 high-power fields.