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World J Gastroenterol. Apr 21, 2014; 20(15): 4382-4392
Published online Apr 21, 2014. doi: 10.3748/wjg.v20.i15.4382
Published online Apr 21, 2014. doi: 10.3748/wjg.v20.i15.4382
Effect of resistance training on non-alcoholic fatty-liver disease a randomized-clinical trial
Shira Zelber-Sagi, Assaf Buch, Hanny Yeshua, Nahum Vaisman, Muriel Webb, Naomi Fliss-Isakov, Elena Izkhakov, Zamir Halpern, Erwin Santo, Ran Oren, Oren Shibolet, Department of Gastroenterology, Tel Aviv Medical Center, 6423906 Tel-Aviv, Israel
Shira Zelber-Sagi, Gil Harari, School of Public Health, University of Haifa, 3498838 Haifa, Israel
Assaf Buch, Hanny Yeshua, Nahum Vaisman, Naomi Fliss-Isakov, Zamir Halpern, Erwin Santo, Ran Oren, Oren Shibolet, The Sackler Faculty of Medicine, Tel-Aviv University, 6997801 Tel Aviv, Israel
Ofer Kis, Wingate Institute for Physical Education and Sport, 4290200 Netanya, Israel
Author contributions: Zelber-Sagi S conceived the study; Zelber-Sagi S and Buch A designed the study; Zelber-Sagi S, Buch A and Harari G analyzed the data; Zelber-Sagi S, Buch A and Yeshua H performed the data collection; Vaisman N, Webb M, Kis O, Fliss-Isakov N, Izkhakov E helped in data collection; Halpern Z, Santo E, Oren R and Shibolet O conducted on data collection; Zelber-Sagi S, Buch A and Shibolet O wrote the manuscript; all authors critically reviewed the manuscript and approved it.
Correspondence to: Shira Zelber-Sagi, PhD, Department of Gastroenterology, Tel Aviv Medical Center, 6 Weizman st., 6423906 Tel-Aviv, Israel. zelbersagi@bezeqint.net
Telephone: +972-3-6973984 Fax: +972-3-6974622
Received: September 25, 2013
Revised: January 6, 2014
Accepted: January 19, 2014
Published online: April 21, 2014
Revised: January 6, 2014
Accepted: January 19, 2014
Published online: April 21, 2014
Core Tip
Core tip: Resistance training is viewed as a complement to aerobic training. However, data on the effect of resistance training on non alcoholic liver disease (NAFLD) is scant. A three month resistance training in NAFLD patients exerted a significant reduction in liver fat as well as reduction in total body and trunk fat with increase in lean body mass. Furthermore, resistance training led to reduction in serum ferritin and cholesterol. In NAFLD patients, compliance to aerobic training may be low due to fatigue. Therefore, resistance training can serve as an easier alternative or a complement form of exercise in these patients.