Zavoral M, Suchanek S, Majek O, Fric P, Minarikova P, Minarik M, Seifert B, Dusek L. Colorectal cancer screening: 20 years of development and recent progress. World J Gastroenterol 2014; 20(14): 3825-3834 [PMID: 24744575 DOI: 10.3748/wjg.v20.i14.3825]
Corresponding Author of This Article
Miroslav Zavoral, MD, PhD, Professor, Chief, Department of Medicine, 1st Faculty of Medicine, Military University Hospital, Charles University, U Vojenske Nemocnice 1200, Prague 6, CZ 169 02 Prague, Czech Republic. miroslav.zavoral@uvn.cz
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Topic Highlight
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World J Gastroenterol. Apr 14, 2014; 20(14): 3825-3834 Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.3825
Colorectal cancer screening: 20 years of development and recent progress
Miroslav Zavoral, Stepan Suchanek, Ondrej Majek, Premysl Fric, Petra Minarikova, Marek Minarik, Bohumil Seifert, Ladislav Dusek
Miroslav Zavoral, Stepan Suchanek, Premysl Fric, Petra Minarikova, Department of Medicine, 1st Faculty of Medicine, Military University Hospital, Charles University, CZ 169 02 Prague, Czech Republic
Ondrej Majek, Ladislav Dusek, Institute of Biostatistics and Analyses, Masaryk University, CZ 602 00 Brno, Czech Republic
Marek Minarik, Genomac Research Institute, Centre for Applied Genomics of Solid Tumors, CZ 161 00 Prague, Czech Republic
Bohumil Seifert, Institute of General Medicine, 1st Faculty of Medicine, Charles University, CZ 128 00 Prague, Czech Republic
Author contributions: Zavoral M, Suchanek S, Majek O and Fric P contributed to the initial draft and data collection; Minarikova P and Minarik M revised the manuscript; Seifert B and Dusek L contributed to the overall scientific supervision and revision.
Supported by The Intern Grant Agency of the Czech Ministry of Health (IGA), No. NT 13673-4
Correspondence to: Miroslav Zavoral, MD, PhD, Professor, Chief, Department of Medicine, 1st Faculty of Medicine, Military University Hospital, Charles University, U Vojenske Nemocnice 1200, Prague 6, CZ 169 02 Prague, Czech Republic. miroslav.zavoral@uvn.cz
Telephone: +420-97-3203061 Fax: +420-97-3203068
Received: September 22, 2013 Revised: November 22, 2013 Accepted: January 6, 2014 Published online: April 14, 2014
Core Tip
Core tip: The rising incidence rate of colorectal cancer (CRC) puts demands on systematic approaches towards secondary prevention. The National CRC Screening Program in the Czech Republic has been running for more than 13 years. Nowadays, guaiac and immunochemical fecal occult blood tests (FOBT) are used, as well as screening colonoscopy. The quality control system was devised with the introduction of CRC Screening Registry. Since 2006, 104565 preventive colonoscopies have been performed: 89752 FOBT+ colonoscopies (85.8%) and 14813 screening colonoscopies (14.2%). Adenomas were diagnosed in 30515 patients undergoing FOBT+ colonoscopy (34.0%), and in 3719 patients through screening colonoscopy (25.1%). In all preventive colonoscopies, a total of 4193 cancers were registered.
