Meta-Analysis
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World J Gastroenterol. Apr 7, 2014; 20(13): 3680-3692
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3680
Evidence based medicine and surgical approaches for colon cancer: Evidences, benefits and limitations of the laparoscopic vs open resection
Laura Lorenzon, Marco La Torre, Vincenzo Ziparo, Francesco Montebelli, Paolo Mercantini, Genoveffa Balducci, Mario Ferri
Laura Lorenzon, Marco La Torre, Vincenzo Ziparo, Francesco Montebelli, Paolo Mercantini, Genoveffa Balducci, Mario Ferri, Surgical and Medical Department of Translational Medicine, Sant’Andrea Hospital, Faculty of Medicine and Psychology University of Rome “La Sapienza”, 00189 Rome, Italy
Author contributions: Lorenzon L, La Torre M, Ziparo V and Ferri M designed the manuscript; Lorenzon L, Montebelli F and Mercantini P performed the database search; Montebelli F, Mercantini P and Balducci G assessed manuscripts for inclusion/exclusion; Lorenzon L, Ziparo V, Mercantini P and Balducci G performed the systematic review; Lorenzon L, La Torre M and Ferri M performed the meta-analysis; Lorenzon L, La Torre M and Ferri M wrote the paper; all authors have reviewed and approved the manuscript in its final form.
Supported by The PhD University Grant program “Clinical and Experimental Research Methodologies in Oncology” provided by the Faculty of Medicine and Psychology University of Rome “La Sapienza” to La Torre M
Correspondence to: Laura Lorenzon, MD, PhD, Surgical and Medical Department of Translational Medicine, Sant’Andrea Hospital, Faculty of Medicine and Psychology University of Rome “La Sapienza”, Via di Grottarossa 1035-39, 00189 Rome, Italy. laura.lorenzon@uniroma1.it
Telephone: +39-633-775989 Fax: +39-633-775322
Received: September 29, 2013
Revised: December 26, 2013
Accepted: February 17, 2014
Published online: April 7, 2014
Core Tip

Core tip: This is a comprehensive meta-analysis of studies investigating laparoscopic resection in comparison with the open surgery for colon cancer, with the aim of evidencing short term and long term results of the surgical approaches. Results were provided according to the study designs (randomized trials, case control series) and according to the tumor’s location.