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World J Gastroenterol. Mar 28, 2014; 20(12): 3164-3172
Published online Mar 28, 2014. doi: 10.3748/wjg.v20.i12.3164
Published online Mar 28, 2014. doi: 10.3748/wjg.v20.i12.3164
Microscopic features of colorectal neoplasia in inflammatory bowel diseases
Aude Bressenot, Virginie Cahn, Department of pathology, University Hospital of Nancy, 54500 Vandoeuvre-lès-Nancy, France
Silvio Danese, IBD Center, Division of Gastroenterology, Humanitas Clinical and Research Center, 20089 Milan, Italy
Laurent Peyrin-Biroulet, Inserm U954 and Department of Hepato-Gastroenterology, University Hospital of Nancy, 54500 Vandoeuvre-lès-Nancy, France
Author contributions: Bressenot A wrote the first draft of the article; Cahn V provided figures and critical revision of the manuscript; Danese S provided critical revision of the manuscript; Peyrin-Biroulet L contributed to editing of the manuscript and supervised the work.
Correspondence to: Laurent Peyrin-Biroulet, Professor, Inserm U954 and Department of Hepato-Gastroenterology, University Hospital of Nancy, Allée du Morvan, 54500 Vandoeuvre-lès-Nancy, France. peyrinbiroulet@gmail.com
Telephone: +33-3-83153661 Fax: +33-3-83153633
Received: July 31, 2013
Revised: December 20, 2013
Accepted: January 19, 2014
Published online: March 28, 2014
Revised: December 20, 2013
Accepted: January 19, 2014
Published online: March 28, 2014
Core Tip
Core tip: The risk of developing dysplasia leading to colorectal cancer is increased in both ulcerative colitis and Crohn’s disease. The biopsy interpretations will guide decision making in clinical practice: colonoscopic surveillance or surgical management. This review summarizes histological features of dysplasia and colorectal cancer in inflammatory bowel disease.