Brief Article
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World J Gastroenterol. Mar 14, 2014; 20(10): 2688-2694
Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2688
Association of CD14/-260 polymorphism with gastric cancer risk in Highland Tibetans
Kang Li, Zeng Dan, Xue-Jun Hu, Luo-Bu Gesang, Yong-Ge Ze, Zha-Xi Bianba, Cuo-Mu Ciren, Yu-Qiang Nie
Kang Li, Zeng Dan, Xue-Jun Hu, Luo-Bu Gesang, Department of Gastroenterology, People’s Hospital of Tibet Autonomous Region, Lhasa 850000, Tibet Autonomous Region, China
Yong-Ge Ze, Zha-Xi Bianba, Cuo-Mu Ciren, Department of Oncology, People’s Hospital of Tibet Autonomous Region, Lhasa 850000, Tibet Autonomous Region, China
Yu-Qiang Nie, Department of Gastroenterology, Guangzhou First People’s Hospital, Guangzhou Medical University, Guangzhou 510180, Guangdong Province, China
Author contributions: Li K, Dan Z, Hu XJ and Gesang LB contributed equally to this work; Li K, Dan Z, Hu XJ, Gesang LB and Nie YQ designed the study; Li K, Ze YG, Bianba ZX and Ciren CM performed the research; Hu XJ and Gesang LB analyzed the data; Li K, Dan Z and Nie YQ wrote the manuscript.
Supported by National Natural Science Foundation of China, No. 81060165
Correspondence to: Dr. Kang Li, Department of Gastroenterology, People’s Hospital of Tibet Autonomous Region, 18 North Lin Kuo Road, Lhasa 850000, Tibet Autonomous Region, China. likang820@aliyun.com
Telephone: +86-891-6333324 Fax: +86-891-6371511
Received: August 29, 2013
Revised: November 28, 2013
Accepted: January 2, 2014
Published online: March 14, 2014
Core Tip

Core tip: This is the first study to report that CD14 gene polymorphisms in Highland Tibetans are associated with gastric cancer risk. We also identified a biomarker that can be used in gastric cancer research and clinical practice.