Brief Article
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World J Gastroenterol. Dec 21, 2013; 19(47): 9043-9048
Published online Dec 21, 2013. doi: 10.3748/wjg.v19.i47.9043
Small bowel tumors detected and missed during capsule endoscopy: Single center experience
Edyta S Zagorowicz, Anna M Pietrzak, Ewa Wronska, Jacek Pachlewski, Piotr Rutkowski, Ewa Kraszewska, Jaroslaw Regula
Edyta S Zagorowicz, Anna M Pietrzak, Ewa Wronska, Jacek Pachlewski, Ewa Kraszewska, Jaroslaw Regula, Department of Gastroenterology, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 02-781 Warsaw, Poland
Piotr Rutkowski, Department of Soft Tissue/Bone Sarcoma and Melanoma, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 02-781 Warsaw, Poland
Edyta S Zagorowicz, Anna M Pietrzak, Ewa Wronska, Jacek Pachlewski, Ewa Kraszewska, Jaroslaw Regula, Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, 01-813 Warsaw, Poland
Author contributions: Zagorowicz ES and Pietrzak AM were responsible for the conception and design of the study, data collection and analysis, drafting the manuscript, and its final approval; Wronska E, Pachlewski J and Zagorowicz ES performed the endoscopic procedures analyzed in the study; Rutkowski P was responsible for GIST data collection and analysis; Kraszewska E was responsible for the statistical analysis and interpretation of the results; Regula J contributed to the study design and critically revised the article for important intellectual content; All the authors were involved in writing the manuscript.
Supported by The Polish Foundation for Gastroenterology
Correspondence to: Anna M Pietrzak, MD, Department of Gastroenterology, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 5 Roentgen Street, 02-781 Warsaw, Poland. anpietrzak@gmail.com
Telephone: +48-22-5462328 Fax: +48-22-5463035
Received: July 17, 2012
Revised: September 12, 2013
Accepted: September 16, 2013
Published online: December 21, 2013
Core Tip

Core tip: The aims of this study were to characterize small bowel (SB) tumors detected by capsule endoscopy (CE) and identify SB tumors missed by CE. The study included 150 consecutive CE investigations. Following CE, the medical records of the study population were reviewed and the patients contacted by telephone or postal mail. National cancer registries were searched to identify missed neoplasms. CE detected 15 SB tumors (10%). During the follow-up period, three additional SB tumors were found. The sensitivity of CE for tumor detection was 83.3% and the negative predictive value 97.6%. The specificity and positive predictive value were both 100%.