Published online Dec 21, 2013. doi: 10.3748/wjg.v19.i47.8974
Revised: August 29, 2013
Accepted: September 16, 2013
Published online: December 21, 2013
Core tip: This review offers a state-of-the-art discussion on the long-term consequences of Giardia infections, the most common waterborne parasitic infection of the human intestine worldwide, from extra-intestinal manifestations, growth and cognitive deficiencies, to post-infectious irritable bowel syndrome. The discussion also sheds light on some of the novel mechanisms recently implicated in the production of these post-infectious manifestations.