Published online Dec 21, 2013. doi: 10.3748/wjg.v19.i47.8924
Revised: October 30, 2013
Accepted: November 28, 2013
Published online: December 21, 2013
Core tip: The clinical relevance of interleukin 28B genotyping in patients with hepatitis C virus genotype 2 and 3 infection is debated. In this critical analysis of studies performed so far, it was shown that this genetic tool may help in optimizing treatment of genotype 3 patients, whilst it plays a marginal role in genotype 2 infected patients management.