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World J Gastroenterol. Dec 14, 2013; 19(46): 8595-8604
Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8595
Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8595
Intraductal papillary neoplasm of the bile duct
Xue-Shuai Wan, Yi-Yao Xu, Jun-Yan Qian, Xiao-Bo Yang, An-Qiang Wang, Lian He, Hai-Tao Zhao, Xin-Ting Sang, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Author contributions: Wan XS, Xu YY contributed equally to this work in writing and revising the manuscript; Qian JY, Yang XB were involved in editing the manuscript; Wang AQ, He L generated the tables and contributed to the writing of the manuscript; Zhao HT, Sang XT contributed equally to the concept and design of this review.
Supported by The National Natural Science Foundation of China, No. 30970623 and No.31071137; International Science and Technology Cooperation Projects, No. 2010DFA31840 and No. 2010DFB33720; Program for New Century Excellent Talents in University, No. NCET-11-0288; and Beijing Natural Science Foundation, No. 5112030
Correspondence to: Xin-Ting Sang, MD, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Wangfujing, Beijing 100730, China. sangxinting@qq.com
Telephone: +86-10-69156042 Fax: +86-10-69156043
Received: June 29, 2013
Revised: September 7, 2013
Accepted: September 29, 2013
Published online: December 14, 2013
Revised: September 7, 2013
Accepted: September 29, 2013
Published online: December 14, 2013
Core Tip
Core tip: In this review, we have provided a more comprehensive understanding of “intraductal papillary neoplasm of the bile duct” than in other research articles. We found that preoperative pathologic diagnosis by biopsy could not reflect the actual stage in many cases because different foci might be of different stages and because mixed pathologic findings might exist in the same lesion. Staging, histologic subtype, curative resection and lymph node metastasis were factors affecting long-term survival.