Review
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World J Gastroenterol. Nov 28, 2013; 19(44): 7972-7982
Published online Nov 28, 2013. doi: 10.3748/wjg.v19.i44.7972
Alcoholism and liver disease in Mexico: Genetic and environmental factors
Sonia Roman, Eloy Alfonso Zepeda-Carrillo, Laura Eugenia Moreno-Luna, Arturo Panduro
Sonia Roman, Eloy Alfonso Zepeda-Carrillo, Laura Eugenia Moreno-Luna, Arturo Panduro, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, “Fray Antonio Alcalde” and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico
Eloy Alfonso Zepeda-Carrillo, Universidad Autónoma de Nayarit and Hospital Civil Tepic “Antonio González Guevara”, Tepic, Nayarit 63000, Mexico
Author contributions: Roman S and Zepeda-Carrillo EA contributed equally to drafting the manuscript, acquiring the data and critically revising the article; Moreno-Luna LE contributed to acquiring and analyzing the data; Panduro A conceived and drafted the manuscript, analyzed the data and critically revised the manuscript; all of the authors revised and approved the final version.
Supported by The National Council of Science and Technology, (Conacyt-Fondo Sectorial, Mexico), Grant No. Salud-2010-1-139085 awarded to Roman S
Correspondence to: Arturo Panduro, MD, PhD, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, “Fray Antonio Alcalde” and Health Sciences Center, University of Guadalajara, Hospital 278, Col. El Retiro, Guadalajara, Jalisco 44280, Mexico. apanduro@prodigy.net.mx
Telephone: +52-33-36147743 Fax: +52-33-36147743
Received: June 29, 2013
Revised: August 15, 2013
Accepted: October 17, 2013
Published online: November 28, 2013
Core Tip

Core tip: Alcoholism and liver disease are leading global health problems. However, the severity and outcome of liver disease appear to vary between individuals and populations. In the present review, we analyze the general scope of alcohol consumption and its relationship with the pattern of drinking score in different countries. We focus on the development of alcoholism in Mexico, which has a strong historical background, and emphasize the need to understand the genetic and environmental factors affecting each population or geographical region of the world.