Published online Oct 21, 2013. doi: 10.3748/wjg.v19.i39.6689
Revised: August 10, 2013
Accepted: September 13, 2013
Published online: October 21, 2013
Core tip: Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. The preoperative diagnosis of BMPM is difficult, and final diagnosis requires histological evaluation of a surgical specimen. In immunohistochemical analysis, positive expression of mesothelial cells and calretinin is always noted. The best treatment strategy for BMPM is en bloc removal, which can avoid recurrence. The recurrent rate after complete resection is about 50%; the recurrent tumor should be completely removed and follow-up including physical examination and imaging studies is required for all cases.