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World J Gastroenterol. Sep 28, 2013; 19(36): 6098-6107
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6098
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6098
Helicobacter pylori infection and esophageal cancer risk: An updated meta-analysis
Fa-Jun Xie, Yi-Ping Zhang, Lan Shao, Xin-Min Yu, Department of Medical Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, Zhejiang Province, China
Fa-Jun Xie, Qiu-Qing Zheng, Ming Chen, De-Hong Zou, Wei-Min Mao, Zhejiang Key Laboratory of Diagnosis and Treatment Technology on Thoracic Oncology (Lung and Esophagus), Hangzhou 310022, Zhejiang Province, China
Hong-Chuan Jin, Fa-Liang Wang, Laboratory of Cancer Biology, Sir Runrun Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310029, Zhejiang Province, China
Author contributions: Xie FJ and Mao WM designed research; Zheng QQ and Wang FL collected and analyzed the data; Zhang YP and Shao L wrote the manuscript; Zou DH and Yu XM contributed to the discussion; Chen M and Jin HC contributed to the discussion and revised the manuscript.
Supported by China Postdoctoral Science Foundation, No. 2012M521189; Zhejiang Provincial Postdoctoral Science Foundation, No. Bsh1202064; National Natural Science Foundation of China, No. 81172081; Zhejiang Provincial Natural Science Foundation, No. LY13H160024; and Wu Jieping Medical Foundation, No. 2011, 3206750.11059 and 11091
Correspondence to: Wei-Min Mao, Professor, Zhejiang Key Laboratory of Diagnosis and Treatment Technology on Thoracic Oncology (Lung and Esophagus), No. 38 Guangji Road, Banshanqiao District, Hangzhou 310022, Zhejiang Province, China. maowm1318@163.com
Telephone: +86-571-88122182 Fax: +86-571-88122181
Received: June 14, 2013
Revised: July 29, 2013
Accepted: August 12, 2013
Published online: September 28, 2013
Revised: July 29, 2013
Accepted: August 12, 2013
Published online: September 28, 2013
Core Tip
Core tip: Based on this meta-analysis, we found that Helicobacter pylori infection may have a protective effect against esophageal squamous cell carcinoma in Eastern populations and against esophageal adenocarcinoma in the overall population.