Published online Aug 21, 2013. doi: 10.3748/wjg.v19.i31.5187
Revised: June 7, 2013
Accepted: June 18, 2013
Published online: August 21, 2013
Core tip: We described a case of primary gastric choriocarcinoma with a complete response to multidisciplinary treatment including surgery, chemotherapy, and radiofrequency ablation (RFA). The patient has been alive with no evidence of disease for 10 years. To the best of our knowledge, this patient with recurrent primary gastric choriocarcinoma has achieved the longest survival. The present case is the first report of choriocarcinoma metastatic to the lung successfully treated with RFA. From our retrospective analysis of recurrent or unresectable primary gastric choriocarcinoma, we propose that gonadal choriocarcinoma regimens can be considered as first-line for primary gastric choriocarcinoma.